Clinical

EQUIP study reports 2.5-minute total-body PET/CT

The 25-patient oncology comparison found an 83% acquisition-time reduction and higher reader scores for image quality on a 128-cm long-axial field-of-view PET/CT system.

A 25-patient oncology imaging study reported 2.5-minute PET/CT acquisitions on a 128-cm long-axial field-of-view system, compared with about 15 minutes on conventional short-axial field-of-view PET/CT scanners.

The EQUIP study compared GE HealthCare’s Omni 128 cm PET/CT with conventional systems, including GE HealthCare Discovery 710 and Siemens Healthineers Vision 600 scanners. Patients underwent both scans after a single radiotracer administration.

Radiotracers included 18F-FDG, 18F-DCFPyL, 68Ga-DOTATATE and 68Ga-PSMA. The long-axial scan used a 10-minute list-mode acquisition that was rebinned to match the short-axial per-bed acquisition times for comparison.

Three nuclear medicine specialists assessed image quality. Reader scores favored the long-axial system across noise, sharpness and lesion conspicuity, according to the abstract.

The authors also reported higher lesion detection with the 128-cm system. Smaller additional lesions were identified in 68% of patients compared with the short-axial scans.

“Long-axis field-of-view PET/CT offers increased sensitivity,” the authors wrote, adding that the approach may shorten acquisition time while maintaining or improving diagnostic image quality.

GE HealthCare describes the Omni 128 cm PET/CT as a system with digital bismuth germanate detectors, 405 cps NEMA sensitivity and 128-cm axial field-of-view coverage for vertex-to-thigh acquisition in a single bed position.

The finding remains early clinical evidence. EQUIP was a small intra-individual comparison, and some differences may reflect scanner design and detector materials rather than axial field-of-view alone.

total-body PETlong-axial field-of-view PET/CTOmni 128 cm PET/CTSNMMI 2026oncology imagingradiotracers
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